7. Chad Michael Murray and Sophia Bush
One Tree Hill is one of the stand-out teen dramas from the early 2000s. When co-stars Chad Michael Murray and Sophia Bush announced that they were dating shortly after the series premiere, it seemed that life was imitating art. The couple even got married in 2005 and it seemed like a happily ever after story to fans.
However, the couple announced their split just five months into their marriage. Bush filed for an annulment due to “fraud,” but was pretty tight-lipped about details. Despite any hard feelings or awkward moments, the two were able to put feelings aside and continue to work together on One Tree Hill until its final season in 2012.